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The principal endpoint was the intraindividual adjust in HbA1c from baseline in response to semaglutide or dapagliflozin in participants with SIDD compared to People with SIRD. It was analysed employing an analysis of covariance model. The model involved the metformin dose and HbA1c at baseline and an interaction expression with the study drug (semaglutide or dapagliflozin) and subgroup (SIDD or SIRD).
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We made use of XGBoost (Extraordinary gradient boosting), an ensemble device Studying method dependant on many sequential selection trees, to identify constant baseline variables predicting the modify in HbA1c, BMI and systolic blood pressure level just after remedy Using the examine drugs. The method develops a multivariable ensemble of prediction types used to establish the strongest predictors.
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